Affinities of β-Lactams for Penicillin Binding Proteins of Chlamydia trachomatis and Their Antichlamydial Activities

Binding affinities of β-lactam antibiotics for the three penicillin binding proteins (PBPs) from Chlamydia trachomatis were determined in vitro and compared with their antichlamydial activities. Mecillinam selectively inhibited PBP1, with a 50% inhibitory concentration for PBP1 binding (0.2 μg/ml) s...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Storey, Christopher, Chopra, Ian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.303-305.2001
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