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Affinities of β-Lactams for Penicillin Binding Proteins of Chlamydia trachomatis and Their Antichlamydial Activities

Binding affinities of β-lactam antibiotics for the three penicillin binding proteins (PBPs) from Chlamydia trachomatis were determined in vitro and compared with their antichlamydial activities. Mecillinam selectively inhibited PBP1, with a 50% inhibitory concentration for PBP1 binding (0.2 μg/ml) s...

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Bibliografiske detaljer
Main Authors: Storey, Christopher, Chopra, Ian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90278/
https://ncbi.nlm.nih.gov/pubmed/11120983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.303-305.2001
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