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In Vitro and In Vivo Antibacterial Activities of L-084, a Novel Oral Carbapenem, against Causative Organisms of Respiratory Tract Infections

L-084 (a prodrug of LJC 11,036 [L-036]) is a new oral carbapenem. Here we compared the in vitro and in vivo antibacterial activities of L-036 with those of imipenem, faropenem, ceditoren-pivoxil, cefdinir, amoxicillin, and levofloxacin. The MICs at which 90% of the isolates were inhibited of L-036 a...

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Autori principali: Miyazaki, Shuichi, Hosoyama, Takayuki, Furuya, Nobuhiko, Ishii, Yoshikazu, Matsumoto, Tetsuya, Ohno, Akira, Tateda, Kazuhiro, Yamaguchi, Keizo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90261/
https://ncbi.nlm.nih.gov/pubmed/11120966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.203-207.2001
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