In Vitro and In Vivo Antibacterial Activities of L-084, a Novel Oral Carbapenem, against Causative Organisms of Respiratory Tract Infections

L-084 (a prodrug of LJC 11,036 [L-036]) is a new oral carbapenem. Here we compared the in vitro and in vivo antibacterial activities of L-036 with those of imipenem, faropenem, ceditoren-pivoxil, cefdinir, amoxicillin, and levofloxacin. The MICs at which 90% of the isolates were inhibited of L-036 a...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Miyazaki, Shuichi, Hosoyama, Takayuki, Furuya, Nobuhiko, Ishii, Yoshikazu, Matsumoto, Tetsuya, Ohno, Akira, Tateda, Kazuhiro, Yamaguchi, Keizo
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Susceptibility
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90261/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.203-207.2001
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