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Molecular Modeling Approach to Understanding the Mode of Action of l-Nucleosides as Antiviral Agents
A series of unnatural l-nucleosides such as 3TC, FTC and l-FMAU have been found to be potent antiviral agents. The mode of action of l-nucleosides has been found to be similar to that of d-nucleosides as antiviral agents, despite their unnatural stereochemistry, that is, nucleotide formation by kina...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90251/ https://ncbi.nlm.nih.gov/pubmed/11120956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.138-144.2001 |
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