Clarithromycin Inhibits NF-κB Activation in Human Peripheral Blood Mononuclear Cells and Pulmonary Epithelial Cells

Macrolide antibiotics modulate the production of proinflammatory cytokines in vivo and in vitro. Transcription of the genes for these proinflammatory cytokines is regulated by nuclear factor κB (NF-κB). We examined whether or not clarithromycin inhibits the activation of NF-κB induced by tumor necro...

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Detalhes bibliográficos
Main Authors: Ichiyama, Takashi, Nishikawa, Miki, Yoshitomi, Tomomi, Hasegawa, Shunji, Matsubara, Tomoyo, Hayashi, Takashi, Furukawa, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Biologic Response Modifiers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90237/
https://ncbi.nlm.nih.gov/pubmed/11120942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.44-47.2001
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