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Erythromycin Inhibits Transcriptional Activation of NF-κB, but not NFAT, through Calcineurin-Independent Signaling in T Cells

The molecular mechanism of the anti-inflammatory effect of erythromycin (EM) was investigated at the level of transcriptional regulation of cytokine gene expression in T cells. EM (>10(−6) M) significantly inhibited interleukin-8 (IL-8) expression but not IL-2 expression from T cells induced with...

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Detalhes bibliográficos
Main Authors: Aoki, Yosuke, Kao, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89542/
https://ncbi.nlm.nih.gov/pubmed/10543746
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