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Use of Molecular Beacons To Detect an Antifolate Resistance-Associated Mutation in Plasmodium falciparum

A PCR-based technique using new fluorescent probes, called molecular beacons, was developed to detect the antifolate resistance-associated S108N point mutation in Plasmodium falciparum. One hundred African clinical isolates were tested by the new method in comparison with the PCR-restriction fragmen...

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Autori principali: Durand, Rémy, Eslahpazire, Jobin, Jafari, Sayeh, Delabre, Jean-François, Marmorat-Khuong, Anne, di Piazza, Jean-Philippe, Le Bras, Jacques
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90225/
https://ncbi.nlm.nih.gov/pubmed/11083660
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