Mutant Prevention Concentration as a Measure of Fluoroquinolone Potency against Mycobacteria

Mutant prevention concentration (MPC) has been proposed as a new measure of antibiotic potency by which the ability to restrict selection of resistant mutants is evaluated. To determine whether MPC provides potency information unavailable from the more customary measurement of the MIC, 18 fluoroquin...

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Main Authors: Sindelar, Georg, Zhao, Xilin, Liew, Anthony, Dong, Yuzhi, Lu, Tao, Zhou, Jianfeng, Domagala, John, Drlica, Karl
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC90202/
https://ncbi.nlm.nih.gov/pubmed/11083637
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