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[(1)N,(12)N]Bis(Ethyl)-cis-6,7-Dehydrospermine: a New Drug for Treatment and Prevention of Cryptosporidium parvum Infection of Mice Deficient in T-Cell Receptor Alpha

Cryptosporidium parvum infection of T-cell receptor alpha (TCR-α)-deficient mice results in a persistent infection. In this study, treatment with a polyamine analogue (SL-11047) prevented C. parvum infection in suckling TCR-α-deficient mice and cleared an existing infection in older mice. Treatment...

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Main Authors: Waters, W. R., Frydman, B., Marton, L. J., Valasinas, A., Reddy, V. K., Harp, J. A., Wannemuehler, M. J., Yarlett, N.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC90173/
https://ncbi.nlm.nih.gov/pubmed/10991882
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