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Cryptosporidium parvum Initiates Inflammatory Bowel Disease in Germfree T Cell Receptor-α-Deficient Mice

Flora-bearing mice with targeted disruption of T cell receptor (TCR)-α or -β genes spontaneously develop intestinal inflammation with features similar to ulcerative colitis in humans. TCR-α-deficient mice maintained germfree or colonized with a limited number of intestinal bacteria failed to develop...

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Bibliografiske detaljer
Main Authors: Sacco, Randy E., Haynes, Joseph S., Harp, James A., Waters, W. Ray, Wannemuehler, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876657/
https://ncbi.nlm.nih.gov/pubmed/9846962
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