Safety, Tolerability, and Pharmacokinetics of Single Oral Doses of BCH-10652 in Healthy Adult Males

Racemic dOTC (BCH-10652) is a novel nucleoside reverse transcriptase inhibitor consisting of two enantiomers of 2′-deoxy-3′-oxa-4′-thiocytidine, (−)dOTC and (+)dOTC, that have both shown activity against human immunodeficiency virus type 1. The objectives of this study were to characterize the safet...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Smith, Patrick F., Forrest, Alan, Ballow, Charles H., Martin, David E., Proulx, Louise
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90156/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10991865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.10.2816-2823.2000
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