Role of the Neurotransmitter Reuptake-Blocking Activity of Antidepressants in Reversing Chloroquine Resistance In Vitro in Plasmodium falciparum

Since the discovery of the chloroquine (CQ) resistance reversal properties of several different, structurally unrelated classes of compounds, including antidepressants, the way is again open to employ the aminoquinoline drugs to combat malaria effectively. In this study, CQ sensitivity was restored...

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Bibliographic Details
Main Authors: Taylor, Dale, Walden, Jason C., Robins, Ashley H., Smith, Peter J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90136/
https://ncbi.nlm.nih.gov/pubmed/10991845
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