pfcrt Allelic Types with Two Novel Amino Acid Mutations in Chloroquine-Resistant Plasmodium falciparum Isolates from the Philippines

Mutations in the pfcrt and pfmdr1 genes have been associated with chloroquine resistance in Plasmodium falciparum. Ten and five mutations, respectively, have been identified in these genes from chloroquine-resistant parasites worldwide. Mutation patterns in pfcrt revealed that chloroquine resistance...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chen, Nanhua, Kyle, Dennis E., Pasay, Cielo, Fowler, Elizabeth V., Baker, Joanne, Peters, Jennifer M., Cheng, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.11.3500-3505.2003
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