pfcrt Allelic Types with Two Novel Amino Acid Mutations in Chloroquine-Resistant Plasmodium falciparum Isolates from the Philippines

Mutations in the pfcrt and pfmdr1 genes have been associated with chloroquine resistance in Plasmodium falciparum. Ten and five mutations, respectively, have been identified in these genes from chloroquine-resistant parasites worldwide. Mutation patterns in pfcrt revealed that chloroquine resistance...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Chen, Nanhua, Kyle, Dennis E., Pasay, Cielo, Fowler, Elizabeth V., Baker, Joanne, Peters, Jennifer M., Cheng, Qin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.11.3500-3505.2003
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