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Evaluation of Nitrofurantoin Combination Therapy of Metronidazole-Sensitive and -Resistant Helicobacter pylori Infections in Mice

The main objectives of this study were to determine whether the nitroreductase enzyme encoded by the rdxA gene of Helicobacter pylori was responsible for reductive activation of nitrofurantoin and whether a triple-therapy regimen with nitrofurantoin was able to eradicate metronidazole-sensitive and...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Jenks, Peter J., Ferrero, Richard L., Tankovic, Jacques, Thiberge, Jean-Michel, Labigne, Agnès
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10991835/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.10.2623-2629.2000
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