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Evaluation of Nitrofurantoin Combination Therapy of Metronidazole-Sensitive and -Resistant Helicobacter pylori Infections in Mice

The main objectives of this study were to determine whether the nitroreductase enzyme encoded by the rdxA gene of Helicobacter pylori was responsible for reductive activation of nitrofurantoin and whether a triple-therapy regimen with nitrofurantoin was able to eradicate metronidazole-sensitive and...

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Detalhes bibliográficos
Main Authors: Jenks, Peter J., Ferrero, Richard L., Tankovic, Jacques, Thiberge, Jean-Michel, Labigne, Agnès
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90126/
https://ncbi.nlm.nih.gov/pubmed/10991835
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