Characterization of a Genetic Element Carrying the Macrolide Efflux Gene mef(A) in Streptococcus pneumoniae

The mef(A) gene from a clinical isolate of Streptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn1207.1, which contained 8 open reading frames. orf2 encodes a resolvase/invertase, and orf5 is a homolog of the macrolide-stre...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Santagati, Maria, Iannelli, Francesco, Oggioni, Marco R., Stefani, Stefania, Pozzi, Gianni
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2585-2587.2000
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