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Characterization of a Genetic Element Carrying the Macrolide Efflux Gene mef(A) in Streptococcus pneumoniae

The mef(A) gene from a clinical isolate of Streptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn1207.1, which contained 8 open reading frames. orf2 encodes a resolvase/invertase, and orf5 is a homolog of the macrolide-stre...

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Bibliographische Detailangaben
Hauptverfasser: Santagati, Maria, Iannelli, Francesco, Oggioni, Marco R., Stefani, Stefania, Pozzi, Gianni
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90116/
https://ncbi.nlm.nih.gov/pubmed/10952626
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