Anti-Toxoplasma Activities of Antiretroviral Drugs and Interactions with Pyrimethamine and Sulfadiazine In Vitro

The anti-Toxoplasma activities of nine antiretroviral drugs were examined in vitro. Nucleoside analogs had no effect on parasite growth, whereas ritonavir and nelfinavir were inhibitory for Toxoplasma, with 50% inhibitory concentrations of 5.4 and 4.0 μg/ml, respectively. None of the antiviral drugs...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Derouin, Francis, Santillana-Hayat, Maud
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Susceptibility
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2575-2577.2000
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