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Anti-Toxoplasma Activities of Antiretroviral Drugs and Interactions with Pyrimethamine and Sulfadiazine In Vitro

The anti-Toxoplasma activities of nine antiretroviral drugs were examined in vitro. Nucleoside analogs had no effect on parasite growth, whereas ritonavir and nelfinavir were inhibitory for Toxoplasma, with 50% inhibitory concentrations of 5.4 and 4.0 μg/ml, respectively. None of the antiviral drugs...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Derouin, Francis, Santillana-Hayat, Maud
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90113/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952623/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2575-2577.2000
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