Successful Trovafloxacin Prophylaxis against Experimental Streptococcal Aortic Valve Endocarditis

Single-dose trovafloxacin (15 mg/kg given intravenously [i.v.]) and ampicillin (40 mg/kg given i.v.) protected 38 and 33% of animals challenged with an ampicillin-tolerant strain of Streptococcus oralis, respectively. As a double-dose regimen, trovafloxacin afforded total protection (100%; P < 0....

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Autori principali: Katsarolis, Ioannis, Pefanis, Angelos, Iliopoulos, Dimitrios, Siaperas, Peter, Karayiannakos, Panagiotis, Giamarellou, Helen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90109/
https://ncbi.nlm.nih.gov/pubmed/10952619
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