Successful Trovafloxacin Prophylaxis against Experimental Streptococcal Aortic Valve Endocarditis

Single-dose trovafloxacin (15 mg/kg given intravenously [i.v.]) and ampicillin (40 mg/kg given i.v.) protected 38 and 33% of animals challenged with an ampicillin-tolerant strain of Streptococcus oralis, respectively. As a double-dose regimen, trovafloxacin afforded total protection (100%; P < 0.001...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Katsarolis, Ioannis, Pefanis, Angelos, Iliopoulos, Dimitrios, Siaperas, Peter, Karayiannakos, Panagiotis, Giamarellou, Helen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2564-2566.2000
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