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Depletion of the Squalene Synthase (ERG9) Gene Does Not Impair Growth of Candida glabrata in Mice

Squalene synthase (farnesyl-diphosphate farnesyltransferase, EC 2.5.1.21) is the first committed enzyme of the sterol biosynthesis pathway. Inhibitors of this enzyme have been intensively studied as potential antifungal agents. To assess the effect of deactivating squalene synthase on the growth of...

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Bibliografiska uppgifter
Huvudupphovsmän: Nakayama, Hironobu, Izuta, Miho, Nakayama, Noboru, Arisawa, Mikio, Aoki, Yuko
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC90078/
https://ncbi.nlm.nih.gov/pubmed/10952588
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