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Depletion of the Squalene Synthase (ERG9) Gene Does Not Impair Growth of Candida glabrata in Mice

Squalene synthase (farnesyl-diphosphate farnesyltransferase, EC 2.5.1.21) is the first committed enzyme of the sterol biosynthesis pathway. Inhibitors of this enzyme have been intensively studied as potential antifungal agents. To assess the effect of deactivating squalene synthase on the growth of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nakayama, Hironobu, Izuta, Miho, Nakayama, Noboru, Arisawa, Mikio, Aoki, Yuko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC90078/
https://ncbi.nlm.nih.gov/pubmed/10952588
Tagiau: Ychwanegu Tag
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