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Functional Analysis of the Active Site of a Metallo-β-Lactamase Proliferating in Japan

An R-plasmid-mediated metallo-β-lactamase was found in Klebsiella pneumoniae DK4 isolated in Japan in 1991. The nucleotide sequence of its structural gene revealed that the β-lactamase termed DK4 was identical to the IMP-1 metallo-β-lactamase which was mediated by a chromosomal gene of Serratia marc...

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Main Authors: Haruta, Shin, Yamaguchi, Hitomi, Yamamoto, Elise Tie, Eriguchi, Yoshiro, Nukaga, Michiyoshi, O'Hara, Koji, Sawai, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90062/
https://ncbi.nlm.nih.gov/pubmed/10952572
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