Biochemical-Genetic Characterization and Distribution of OXA-22, a Chromosomal and Inducible Class D β-Lactamase from Ralstonia (Pseudomonas) pickettii

From genomic DNA of Ralstonia pickettii isolate PIC-1, a β-lactamase gene was cloned that encodes the oxacillinase OXA-22. It differs from known oxacillinases, being most closely related to OXA-9 (38% amino acid identity). The hydrolytic spectrum of OXA-22 is limited mostly to benzylpenicillin, clox...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Nordmann, Patrice, Poirel, Laurent, Kubina, Maryline, Casetta, Anne, Naas, Thierry
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10898703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.8.2201-2204.2000
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