Population Pharmacokinetics and Pharmacodynamic Modeling of Abacavir (1592U89) from a Dose-Ranging, Double-Blind, Randomized Monotherapy Trial with Human Immunodeficiency Virus-Infected Subjects

Abacavir (formerly 1592U89) is a carbocyclic nucleoside analog with potent anti-human immunodeficiency virus (anti-HIV) activity when administered alone or in combination with other antiretroviral agents. The population pharmacokinetics and pharmacodynamics of abacavir were investigated in 41 HIV ty...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Weller, Stephen, Radomski, Kristine M., Lou, Yu, Stein, Daniel S.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Antiviral Agents
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10898675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.8.2052-2060.2000
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