Safety and Single-Dose Pharmacokinetics of Abacavir (1592U89) in Human Immunodeficiency Virus Type 1-Infected Children

Abacavir (formerly 1592U89) is a potent 2′-deoxyguanosine analog reverse transcriptase inhibitor that has been demonstrated to have a favorable safety profile in initial clinical trials with adults with human immunodeficiency virus (HIV) type 1 infection. A phase I study was conducted to evaluate th...

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Autori principali: Hughes, Walter, McDowell, James A., Shenep, Jerry, Flynn, Patricia, Kline, Mark W., Yogev, Ram, Symonds, William, Lou, Yu, Hetherington, Seth
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC89168/
https://ncbi.nlm.nih.gov/pubmed/10049275
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