Safety and Single-Dose Pharmacokinetics of Abacavir (1592U89) in Human Immunodeficiency Virus Type 1-Infected Children

Abacavir (formerly 1592U89) is a potent 2′-deoxyguanosine analog reverse transcriptase inhibitor that has been demonstrated to have a favorable safety profile in initial clinical trials with adults with human immunodeficiency virus (HIV) type 1 infection. A phase I study was conducted to evaluate th...

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Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Hughes, Walter, McDowell, James A., Shenep, Jerry, Flynn, Patricia, Kline, Mark W., Yogev, Ram, Symonds, William, Lou, Yu, Hetherington, Seth
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Pharmacology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.609
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