Mutations at Four Distinct Regions of the rpoB Gene Can Reduce the Susceptibility of Helicobacter pylori to Rifamycins

The transformation of a panel of rpoB mutations (codons 525 to 586) from rifampin-resistant donor strains into Helicobacter pylori 2802A confirmed the MICs associated with the respective mutations. RpoB V149X random mutations were generated and induced different levels of resistance, depending on th...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Heep, Markus, Odenbreit, Stefan, Beck, Daniela, Decker, Jochen, Prohaska, Elke, Rieger, Ulrich, Lehn, Norbert
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Mechanisms of Resistance
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817737/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1713-1715.2000
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