Characterization of a Mycobacterium smegmatis Mutant That Is Simultaneously Resistant to d-Cycloserine and Vancomycin

A mutant of Mycobacterium smegmatis has been isolated that is simultaneously resistant to both d-cycloserine (d-CS) and vancomycin. Genetic complementation with a PBP4 homolog restores sensitivity to both drugs. Resistance to d-CS and vancomycin in this mutant is most likely due to a novel mechanism...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Peteroy, Marcy, Severin, Anatoly, Zhao, Frances, Rosner, Dalya, Lopatin, Uri, Scherman, Hataichanouk, Belanger, Aimee, Harvey, Bohdan, Hatfull, Graham F., Brennan, Patrick J., Connell, Nancy D.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817733/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1701-1704.2000
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