Characterization of a Mycobacterium smegmatis Mutant That Is Simultaneously Resistant to d-Cycloserine and Vancomycin

A mutant of Mycobacterium smegmatis has been isolated that is simultaneously resistant to both d-cycloserine (d-CS) and vancomycin. Genetic complementation with a PBP4 homolog restores sensitivity to both drugs. Resistance to d-CS and vancomycin in this mutant is most likely due to a novel mechanism...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peteroy, Marcy, Severin, Anatoly, Zhao, Frances, Rosner, Dalya, Lopatin, Uri, Scherman, Hataichanouk, Belanger, Aimee, Harvey, Bohdan, Hatfull, Graham F., Brennan, Patrick J., Connell, Nancy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89937/
https://ncbi.nlm.nih.gov/pubmed/10817733
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