Pharmacokinetic Interaction of Abacavir (1592U89) and Ethanol in Human Immunodeficiency Virus-Infected Adults

While in vitro results at clinically relevant concentrations do not predict abacavir (1592U89) interactions with drugs highly metabolized by cytochrome P450, the potential does exist for a pharmacokinetic interaction between abacavir and ethanol, as both are metabolized by alcohol dehydrogenase. Twe...

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Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	McDowell, James A., Chittick, Gregory E., Stevens, Cristina Pilati, Edwards, Kathleen D., Stein, Daniel S.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2000
Предметы:	Antiviral Agents
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1686-1690.2000
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