Comparison of Human Immunodeficiency Virus Type 1 Pr55(Gag) and Pr160(Gag-Pol) Processing Intermediates That Accumulate in Primary and Transformed Cells Treated with Peptidic and Nonpeptidic Protease Inhibitors

Human immunodeficiency virus type 1 (HIV-1) produces two polyproteins, Pr55(Gag) and Pr160(Gag-Pol), that are cleaved into mature functional subunits by the virally encoded protease. Drugs that inhibit this protease are an important part of anti-HIV therapy. We studied the ordered accumulation of Ga...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Speck, R. Renae, Flexner, Charles, Tian, Chun-Juan, Yu, Xiao-Fang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10770790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.5.1397-1403.2000
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