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Efficacy of SCH27899 in an Animal Model of Legionnaires' Disease Using Immunocompromised A/J Mice

The efficacy of SCH27899, a new everninomicin antibiotic, against replicative Legionella pneumophila lung infections in an immunocompromised host was evaluated using a murine model of Legionnaires' disease. A/J mice were immunocompromised with cortisone acetate and inoculated intratracheally with L....

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發表在:Antimicrob Agents Chemother
Principais autores: Brieland, Joan K., Loebenberg, David, Menzel, Fred, Hare, Roberta S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2000
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10770771/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.5.1333-1336.2000
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