Inhibition of Human Rhinovirus-Induced Cytokine Production by AG7088, a Human Rhinovirus 3C Protease Inhibitor

Symptom severity in patients with human rhinovirus (HRV)-induced respiratory illness is associated with elevated levels of the inflammatory cytokines interleukin-6 (IL-6) and IL-8. AG7088 is a novel, irreversible inhibitor of the HRV 3C protease. In this study, AG7088 was tested for its antiviral ac...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Zalman, L. S., Brothers, M. A., Dragovich, P. S., Zhou, R., Prins, T. J., Worland, S. T., Patick, A. K.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Materias:	Antiviral Agents
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89850/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10770757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.5.1236-1241.2000
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