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Single-Dose Pharmacokinetics and Safety of the Oral Antiviral Compound Adefovir Dipivoxil in Children Infected with Human Immunodeficiency Virus Type 1

The acyclic phosphonate analog adefovir is a potent inhibitor of retroviruses, including human immunodeficiency virus (HIV) type 1, and, unlike some antiviral nucleosides, does not require the initial phosphorylation step for its activity. Two oral dosages of the adefovir prodrug adefovir dipivoxil...

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Guardat en:
Publicat a:Antimicrob Agents Chemother
Autors principals: Hughes, Walter T., Shenep, Jerry L., Rodman, John H., Fridland, Arnold, Willoughby, Rodney, Blanchard, Suzette, Purdue, Lynette, Coakley, Dion F., Cundy, Kenneth C., Culnane, Mary, Zimmer, Bonnie, Burchett, Sandra, Read, Jennifer S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89810/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.1041-1046.2000
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