Antimalarial Bioavailability and Disposition of Artesunate in Acute Falciparum Malaria

The pharmacokinetic properties of oral and intravenous artesunate (2 mg/kg of body weight) were studied in 19 adult patients with acute uncomplicated Plasmodium falciparum malaria by using a randomized crossover design. A sensitive bioassay was used to measure the antimalarial activity in plasma whi...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Newton, Paul, Suputtamongkol, Yupin, Teja-Isavadharm, Paktiya, Pukrittayakamee, Sasithon, Navaratnam, V, Bates, Imelda, White, Nicholas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.972-977.2000
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