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Pentamidine Inhibition of Group I Intron Splicing in Candida albicans Correlates with Growth Inhibition

We previously demonstrated that pentamidine, which has been clinically used against Pneumocystis carinii, inhibits in vitro a group I intron ribozyme from that organism. Another fungal pathogen, Candida albicans, also harbors a group I intron ribozyme (Ca.LSU) in the essential rRNA genes in almost h...

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Auteurs principaux: Miletti, Karl E., Leibowitz, Michael J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC89798/
https://ncbi.nlm.nih.gov/pubmed/10722497
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