Compartmental Pharmacokinetics and Tissue Distribution of Multilamellar Liposomal Nystatin in Rabbits

The plasma pharmacokinetics of multilamellar liposomal nystatin were studied in normal, catheterized rabbits after single and multiple daily intravenous administration of dosages of 2, 4, and 6 mg/kg of body weight, and drug levels in tissues were assessed after multiple dosing. Concentrations of li...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Groll, Andreas H., Mickiene, Diana, Werner, Kathy, Petraitiene, Ruta, Petraitis, Vidmantas, Calendario, Myrna, Field-Ridley, Aida, Crisp, Jeremy, Piscitelli, Stephen C., Walsh, Thomas J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Pharmacology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.950-957.2000
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