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Interspecies Comparison of Pharmacokinetics of the Novel Triazole Antifungal Agent SYN-2869 and Its Derivatives

The pharmacokinetics and distribution in tissue of several novel triazole antifungal agents were studied in different animal species in order to select an appropriate lead compound. The purpose of the study was also to determine species differences in pharmacokinetics for SYN azoles to select the mo...

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Main Authors: Khan, Jehangir K., Montaseri, Hashem, Poglod, Marzena, Bu, Hai-Zhi, Zuo, Zhong, Salama, Sameeh M., Daneshtalab, Mohsen, Micetich, Ronald G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89791/
https://ncbi.nlm.nih.gov/pubmed/10722490
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