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Comparative Pharmacokinetics, Tissue Distributions, and Effects on Renal Function of Novel Polymeric Formulations of Amphotericin B and Amphotericin B-Deoxycholate in Rats

The pharmacokinetic profiles of a traditional formulation of amphotericin B (Fungizone) and novel nanosphere and mixed micelle delivery systems developed for amphotericin B were compared and described. Six groups of male Wistar rats received intravenous injections of the different formulations. Plas...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Echevarría, Iciar, Barturen, Celia, Renedo, María Jesús, Trocóniz, Iñaki F., Dios-Viéitez, M. Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.898-904.2000
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