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Comparative Pharmacokinetics, Tissue Distributions, and Effects on Renal Function of Novel Polymeric Formulations of Amphotericin B and Amphotericin B-Deoxycholate in Rats

The pharmacokinetic profiles of a traditional formulation of amphotericin B (Fungizone) and novel nanosphere and mixed micelle delivery systems developed for amphotericin B were compared and described. Six groups of male Wistar rats received intravenous injections of the different formulations. Plas...

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Main Authors: Echevarría, Iciar, Barturen, Celia, Renedo, María Jesús, Trocóniz, Iñaki F., Dios-Viéitez, M. Carmen
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC89789/
https://ncbi.nlm.nih.gov/pubmed/10722488
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