Gemifloxacin Is Effective in Experimental Pneumococcal Meningitis

In a rabbit model of Streptococcus pneumoniae meningitis, 5 mg of gemifloxacin mesylate (SB-265805) per kg/h reduced the bacterial titers in cerebrospinal fluid (CSF) almost as rapidly as 10 mg of ceftriaxone per kg/h (Δlog CFU/ml/h ± standard deviation [SD], −0.25 ± 0.09 versus −0.38 ± 0.11; serum...

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Bibliografiske detaljer
Main Authors: Smirnov, A., Wellmer, A., Gerber, J., Maier, K., Henne, S., Nau, R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89762/
https://ncbi.nlm.nih.gov/pubmed/10681354
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