Synergistic Antifungal Activities of Bafilomycin A(1), Fluconazole, and the Pneumocandin MK-0991/Caspofungin Acetate (L-743,873) with Calcineurin Inhibitors FK506 and L-685,818 against Cryptococcus neoformans

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening infections of the central nervous system. Existing therapies include amphotericin B, fluconazole, and flucytosine, which are limited by toxic side effects and the emergence of drug resistance. We recently demons...

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Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Del Poeta, Maurizio, Cruz, M. Cristina, Cardenas, Maria E., Perfect, John R., Heitman, Joseph
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Susceptibility
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.739-746.2000
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