Synergistic Antifungal Activities of Bafilomycin A(1), Fluconazole, and the Pneumocandin MK-0991/Caspofungin Acetate (L-743,873) with Calcineurin Inhibitors FK506 and L-685,818 against Cryptococcus neoformans

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening infections of the central nervous system. Existing therapies include amphotericin B, fluconazole, and flucytosine, which are limited by toxic side effects and the emergence of drug resistance. We recently demons...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Del Poeta, Maurizio, Cruz, M. Cristina, Cardenas, Maria E., Perfect, John R., Heitman, Joseph
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Susceptibility
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.739-746.2000
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