Enzymes Catalyzing the Early Steps of Clavulanic Acid Biosynthesis Are Encoded by Two Sets of Paralogous Genes in Streptomyces clavuligerus

Genes encoding the proteins required for clavulanic acid biosynthesis and for cephamycin biosynthesis are grouped into a “supercluster” in Streptomyces clavuligerus. Nine open reading frames (ORFs) associated with clavulanic acid biosynthesis were located in a 15-kb segment of the supercluster, incl...

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Autores principales: Jensen, Susan E., Elder, Kenneth J., Aidoo, Kwamena A., Paradkar, Ashish S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Chemistry; Biosynthesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC89753/
https://ncbi.nlm.nih.gov/pubmed/10681345
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