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ampR Gene Mutations That Greatly Increase Class C β-Lactamase Activity in Enterobacter cloacae

The ampC and ampR genes of Enterobacter cloacae GN7471 were cloned into pMW218 to yield pKU403. Four mutant plasmids derived from pKU403 (pKU404, pKU405, pKU406, and pKU407) were isolated in an AmpD mutant of Escherichia coli ML4953 by selection with ceftazidime or aztreonam. The β-lactamase activit...

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Bibliografische gegevens
Hoofdauteurs: Kuga, Akio, Okamoto, Ryoichi, Inoue, Matsuhisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89726/
https://ncbi.nlm.nih.gov/pubmed/10681318
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