In Vitro Antihepadnaviral Activities of Combinations of Penciclovir, Lamivudine, and Adefovir

Penciclovir {9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine [PCV]}, lamivudine ([−]-β-l-2′,3′-dideoxy-3′-thiacytidine [3TC]), and adefovir (9-[2-phosphonylmethoxyethyl]-adenine [PMEA]) are potent inhibitors of hepatitis B virus (HBV) replication. Lamivudine has recently received approval for cl...

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Bibliographic Details
Main Authors: Colledge, Danni, Civitico, Gilda, Locarnini, Stephen, Shaw, Tim
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89725/
https://ncbi.nlm.nih.gov/pubmed/10681317
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