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Consequences of Interaction of a Lipophilic Endotoxin Antagonist with Plasma Lipoproteins

E5531, a novel synthetic lipid A analogue, antagonizes the toxic effects of lipopolysaccharide, making it a potential intravenously administered therapeutic agent for the treatment of sepsis. This report describes the distribution of E5531 in human blood and its activity when it is associated with d...

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Main Authors: Rose, Jeffrey R., Mullarkey, Maureen A., Christ, William J., Hawkins, Lynn D., Lynn, Melvyn, Kishi, Yoshito, Wasan, Kishor M., Peteherych, Kathy, Rossignol, Daniel P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89718/
https://ncbi.nlm.nih.gov/pubmed/10681310
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