Toxicity of LY303366, an Echinocandin Antifungal, in Mice Pretreated with Glucocorticoids

LY303366 is a semisynthetic derivative of the echinocandin class. During preclinical studies, lethal toxicity was observed in DBA/2 mice pretreated with a cortisone acetate dose followed by treatment with LY303366 at doses ranging from 12.5 to 50 mg/kg of body weight/day given intraperitoneally (i.p...

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Detaylı Bibliyografya
Asıl Yazarlar: Clemons, Karl V., Sobel, Raymond A., Stevens, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC89686/
https://ncbi.nlm.nih.gov/pubmed/10639365
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